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Development of a Web-Based Laboratory Class to Reduce the Challenges in Teaching Fragment-Based Drug Design
Journal of Chemical Education ( IF 3 ) Pub Date : 2020-01-09 , DOI: 10.1021/acs.jchemed.9b00198
Xing-Xing Shi 1, 2, 3 , Jing-Yi Li 1, 2 , Qiong Chen 1, 2, 3 , Xiao-Lei Zhu 1, 2, 3 , Ge-Fei Hao 1, 2, 3, 4 , Guang-Fu Yang 1, 2, 3, 5
Affiliation  

Fragment-based drug design (FBDD) is a promising methodology to find quality drug leads. It is important in the curriculum of a drug design course due to its impact on drug discovery. However, teaching FBDD and its use by students remain challenging in most cases. A web-based laboratory class to teach FBDD in the form of our copyrighted workshops is described. The students’ feedback and a quantitative evaluation of the results show that the web-based laboratory class is popular with students and facilitates students’ learning of FBDD for design of possible drug-like molecules.

中文翻译:

开发基于网络的实验室课程,以减少基于片段的药物设计教学中的挑战

基于片段的药物设计(FBDD)是一种寻找高质量药物线索的有前途的方法。由于它对药物发现的影响,因此在药物设计课程的课程中非常重要。但是,在大多数情况下,教授FBDD及其由学生使用仍然具有挑战性。描述了一个基于网络的实验室课程,以我们受版权保护的讲习班的形式教授FBDD。学生的反馈和对结果的定量评估表明,基于网络的实验室课程在学生中很受欢迎,并有助于学生学习FBDD,以设计可能的类药物分子。
更新日期:2020-01-10
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