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Dimensional-Analysis and Similitude for Scale-up of Solid-Liquid Extraction of Eurycoma Longifolia Roots
Chemical Engineering Science ( IF 4.7 ) Pub Date : 2020-05-01 , DOI: 10.1016/j.ces.2020.115490
Noor Hafiza Harun , Azila Abdul-Aziz , Roshanida A. Rahman , Harisun Yaakub , Ramlan Aziz , Ismail Ware

Abstract A dimensionless model was proposed to scale-up the solid-liquid extraction of Eurycoma longifolia roots. ShSc−1 dimensionless number was found to be the best fit of all proposed models. At optimum conditions of the extraction process, which were duration of extraction of 53 min, solvent to raw material ratio of 12.5:1 and roots particle size of 0.5 to 1.0 mm, the extract yield of 8.76% at lab-scale produced ShSc−1 no. of 0.0312. Employing the scale up rule of P/V idem and scale-up factor of 7.65, the extract yield of 8.65% with 1.37% error was obtained at pilot-scale at ShSc−1 no. of 0.0376. The outcome of this study provided useful scale-up knowledge in ensuring smooth transition from lab-scale to pilot-scale.

中文翻译:

长叶桉树根固液萃取放大的量纲分析与相似性

摘要 提出了一种无量纲模型来放大Eurycoma longifolia根的固液提取。发现 ShSc-1 无量纲数是所有建议模型的最佳拟合。在提取过程的最佳条件下,提取时间为 53 分钟,溶剂与原料的比例为 12.5:1,根粒径为 0.5 至 1.0 毫米,实验室规模的提取率为 8.76%,产生了 ShSc-1不。0.0312。采用 P/V idem 的放大规则和放大系数 7.65,在 ShSc-1 号的中试规模下获得了 8.65% 的提取率和 1.37% 的误​​差。0.0376。这项研究的结果提供了有用的放大知识,以确保从实验室规模到中试规模的平稳过渡。
更新日期:2020-05-01
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