An unusual condensation reaction of 2-methyltetrahydroquinazoline N-oxides with aromatic aldehydes was found. The reaction of 4-cyano substituted heterocycles as well as the use of microwave irradiation for 4-morpholinyl substituted heterocycles resulted in the condensation engaging the methylene group of the tetrahydroquinazoline fragment with simultaneous deoxygenation of the N-oxide. A preparative approach towards previously unknown pyrimidine-containing conjugated molecules was developed based on this process.

中文翻译：

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2-甲基四氢喹唑啉1-氧化物与醛的反应性二分法：前所未有的缩合，同时还原N-氧化物片段

发现2-甲基四氢喹唑啉N-氧化物与芳族醛的不寻常的缩合反应。4-氰基取代的杂环的反应以及对4-吗啉基取代的杂环的微波辐射的使用导致缩合与四氢喹唑啉片段的亚甲基结合，同时使N-氧化物脱氧。基于该过程，开发了一种针对先前未知的含嘧啶的共轭分子的制备方法。