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Assessment of Tetrabromobisphenol and Hexabromocyclododecanes exposure and risk characterization using occurrence data in foods.
Food and Chemical Toxicology ( IF 4.3 ) Pub Date : 2020-01-10 , DOI: 10.1016/j.fct.2020.111121
Joon-Goo Lee 1 , Youngjin Jeong 1 , Dongsul Kim 1 , Gil-Jin Kang 1 , Youngwon Kang 1
Affiliation  

Tetrabromobisphenol A (TBBPA) and Hexabromocyclododecanes (HBCDs) are two of the most used BFRs and they have cumulated in the environment. TBBPA and HBCDs in food were determined and their risks were assessed. The analytical method used was validated in different food categories, and the performance parameters were acceptable based on the criteria of AOAC. Fish and cephalopods were contaminated with TBBPA higher than other foods, and fish contained higher levels of HBCDs than other foods. α-HBCD was the predominant diastereomer in fish and meat and had strong correlations with HBCDs in fish and cephalopods. HBCDs accumulated easier than TBBPA in food. People were exposed to TBBPA from 0.125 ng kg-1 b.w. day-1 to 0.284 ng kg-1 b.w. day-1 and HBCDs from 0.353 ng kg-1 b.w. day-1 to 1.006 ng kg-1 b.w. day-1 via food and air. Food mainly contributed to exposure to TBBPA and HBCDs and vegetables were the main contributors for exposure to TBBPA and HBCDs in food. MOEs for the whole population were over 100, and the risks of exposure to TBBPA and HBCDs from food and the environment were of low concern to public health.

中文翻译:

使用食物中的发生数据评估四溴双酚和六溴环十二烷的暴露量和风险特征。

四溴双酚A(TBBPA)和六溴环十二烷(HBCD)是最常用的两种BFR,它们已经在环境中累积。确定了食品中的六溴环十二烷和六溴环十二烷,并评估了它们的风险。所使用的分析方法已在不同食品类别中得到验证,并且根据AOAC的标准,其性能参数是可以接受的。鱼和头足类动物的六溴联苯醚污染程度高于其他食物,鱼类所含六溴环十二烷的含量高于其他食物。α-六溴环十二烷是鱼类和肉类中的主要非对映异构体,与鱼类和头足类中的六溴环十二烷有很强的相关性。食物中的六溴环十二烷比六溴环十二烷更容易积累。人们通过食物和食物接触到从0.125 ng kg-1 bw day-1到0.284 ng kg-1 bw day-1的六溴环十二烷,以及从0.353 ng kg-1 bw day-1到1.006 ng kg-1 bw day-1的六溴环十二烷。空气。食物主要导致接触六溴环十二烷和六溴环十二烷,而蔬菜是食物中接触六溴环十二烷和六溴环十二烷的主要贡献者。整个人口的最低教育水平超过100,食品和环境对TBBPA和HBCD的暴露风险与公共卫生无关紧要。
更新日期:2020-01-11
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