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Healthy lifestyle and life expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study.
The BMJ ( IF 105.7 ) Pub Date : 2020-01-08 , DOI: 10.1136/bmj.l6669
Yanping Li 1 , Josje Schoufour 2, 3 , Dong D Wang 1 , Klodian Dhana 1, 4 , An Pan 5 , Xiaoran Liu 1 , Mingyang Song 1, 6, 7, 8 , Gang Liu 1, 9 , Hyun Joon Shin 10 , Qi Sun 1, 11 , Laila Al-Shaar 1 , Molin Wang 6 , Eric B Rimm 1, 11 , Ellen Hertzmark 12 , Meir J Stampfer 1, 6, 11 , Walter C Willett 1, 6, 11 , Oscar H Franco 2, 13 , Frank B Hu 1, 6, 11
Affiliation  

OBJECTIVE To examine how a healthy lifestyle is related to life expectancy that is free from major chronic diseases. DESIGN Prospective cohort study. SETTING AND PARTICIPANTS The Nurses' Health Study (1980-2014; n=73 196) and the Health Professionals Follow-Up Study (1986-2014; n=38 366). MAIN EXPOSURES Five low risk lifestyle factors: never smoking, body mass index 18.5-24.9, moderate to vigorous physical activity (≥30 minutes/day), moderate alcohol intake (women: 5-15 g/day; men 5-30 g/day), and a higher diet quality score (upper 40%). MAIN OUTCOME Life expectancy free of diabetes, cardiovascular diseases, and cancer. RESULTS The life expectancy free of diabetes, cardiovascular diseases, and cancer at age 50 was 23.7 years (95% confidence interval 22.6 to 24.7) for women who adopted no low risk lifestyle factors, in contrast to 34.4 years (33.1 to 35.5) for women who adopted four or five low risk factors. At age 50, the life expectancy free of any of these chronic diseases was 23.5 (22.3 to 24.7) years among men who adopted no low risk lifestyle factors and 31.1 (29.5 to 32.5) years in men who adopted four or five low risk lifestyle factors. For current male smokers who smoked heavily (≥15 cigarettes/day) or obese men and women (body mass index ≥30), their disease-free life expectancies accounted for the lowest proportion (≤75%) of total life expectancy at age 50. CONCLUSION Adherence to a healthy lifestyle at mid-life is associated with a longer life expectancy free of major chronic diseases.

中文翻译:

健康的生活方式和无癌症、心血管疾病和 2 型糖尿病的预期寿命:前瞻性队列研究。

目的 研究健康的生活方式与没有主要慢性疾病的预期寿命之间的关系。设计前瞻性队列研究。设置和参与者 护士健康研究 (1980-2014; n=73 196) 和卫生专业人员随访研究 (1986-2014; n=38 366)。主要暴露 五种低风险生活方式因素:从不吸烟、体重指数 18.5-24.9、中度至剧烈运动(≥30 分钟/天)、适度饮酒(女性:5-15 克/天;男性 5-30 克/天)天)和更高的饮食质量得分(上 40%)。主要结果 没有糖尿病、心血管疾病和癌症的预期寿命。结果 没有采用低风险生活方式因素的女性在 50 岁时无糖尿病、心血管疾病和癌症的预期寿命为 23.7 年(95% 置信区间为 22.6 至 24.7),相比之下,女性为 34 岁。采用四个或五个低风险因素的女性为 4 年(33.1 至 35.5)。在 50 岁时,没有采用任何低风险生活方式因素的男性的预期寿命为 23.5(22.3 至 24.7)年,而采用 4 或 5 种低风险生活方式因素的男性的预期寿命为 31.1(29.5 至 32.5)年. 对于目前大量吸烟(≥15支/天)或肥胖男性和女性(体重指数≥30)的男性吸烟者,他们的无病预期寿命在50岁时占总预期寿命的比例最低(≤75%) . 结论 中年时坚持健康的生活方式与更长的预期寿命无主要慢性疾病有关。7) 未采用低风险生活方式因素的男性的年龄和采用四或五个低风险生活方式因素的男性的 31.1 年(29.5 至 32.5)年。对于目前大量吸烟(≥15支/天)或肥胖男性和女性(体重指数≥30)的男性吸烟者,他们的无病预期寿命在50岁时占总预期寿命的比例最低(≤75%) . 结论 中年时坚持健康的生活方式与更长的预期寿命无主要慢性疾病有关。7) 未采用低风险生活方式因素的男性的年龄和采用四或五个低风险生活方式因素的男性的 31.1 年(29.5 至 32.5)年。对于目前大量吸烟(≥15支/天)或肥胖男性和女性(体重指数≥30)的男性吸烟者,他们的无病预期寿命在50岁时占总预期寿命的比例最低(≤75%) . 结论 中年时坚持健康的生活方式与更长的预期寿命无主要慢性疾病有关。
更新日期:2020-01-09
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