Dietary prebiotics can be metabolized by different colonic microorganisms and release several classes of metabolites, particularly SCFAs into the intestine lumen, influencing the host physiology. Thus, human microbiota has been the focus of one of the most dynamic research fields of our time and their efforts are directed to understand how prebiotics structures and the microbiota-derived metabolites acts on signaling cell pathways and epigenetic control. Therefore, the aim of this review is to provide an overview about the new concept of prebiotics and their mechanistic local and systemically insights related to the host health.

中文翻译：

---

益生元特性对人类健康的新颖见解：综述

饮食中的益生元可以被不同的结肠微生物代谢，并释放出几类代谢物，尤其是SCFA进入肠腔，影响宿主的生理。因此，人类微生物区系一直是我们这个时代最活跃的研究领域之一，他们的努力旨在了解益生元的结构和微生物来源的代谢产物如何作用于信号传导细胞途径和表观遗传控制。因此，本综述的目的是概述益生元的新概念及其与寄主健康相关的机理性局部和系统性见解。