In this issue of Chem, Zuo and coworkers report an exciting new strategy for the deconstructive functionalization of ketones. Through merging Lewis-acid-catalyzed nucleophilic 1,2-addition and ligand-to-metal charge transfer (LMCT)-promoted C–C cleavage, common strained and unstrained ketones are transformed into synthetically valuable scaffolds with high efficiency under mild conditions.

中文翻译：

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通过LMCT促进的CC裂解，酮的解构功能化

在本期《化学》杂志上，Zuo和同事报告了一种令人兴奋的酮解构功能化新策略。通过合并路易斯酸催化的亲核1,2-加成和配体-金属电荷转移（LMCT）促进的C-C裂解，普通的应变和非应变酮在温和条件下高效转化为合成有价值的支架。