Device-based neuromodulation of brain circuits is emerging as a promising new approach in the study and treatment of psychiatric disorders. This work presents recent advances in the development of tools for identifying neurocircuits as therapeutic targets and in tools for modulating neurocircuits. We review clinical evidence for the therapeutic efficacy of circuit modulation with a range of brain stimulation approaches, including subthreshold, subconvulsive, convulsive, and neurosurgical techniques. We further discuss strategies for enhancing the precision and efficacy of neuromodulatory techniques. Finally, we survey cutting-edge research in therapeutic circuit modulation using novel paradigms and next-generation devices.

中文翻译：

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基于设备的神经回路调节作为精神疾病的治疗方法。

基于设备的脑回路神经调节正在成为精神疾病研究和治疗中一种有希望的新方法。这项工作提出了识别神经回路作为治疗目标的工具和调节神经回路的工具的最新进展。我们审查了一系列脑刺激方法，包括阈下，亚抽搐，抽搐和神经外科技术的电路调制的疗效的临床证据。我们将进一步讨论提高神经调节技术的准确性和功效的策略。最后，我们调查了使用新型范例和下一代设备进行治疗电路调制的前沿研究。