Stem cell-derived sheet engineering has been developed as the next-generation treatment for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem cell transplantation and scaffold tissue engineering. Furthermore, induced pluripotent stem cell-derived cell sheets have been indicated to possess higher potential for MI therapy than other stem cell-derived sheets because of their capacity to form vascularized networks for fabricating thickened human cardiac tissue and their long-term therapeutic effects after transplantation in MI. To date, stem cell sheet transplantation has exhibited a dramatic role in attenuating cardiac dysfunction and improving clinical manifestations of heart failure in MI. In this review, we retrospectively summarized the current applications and strategy of stem cell-derived cell sheet technology for heart tissue repair in MI.

中文翻译：

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干细胞衍生的细胞片移植用于心肌梗死的心脏组织修复。

干细胞衍生的片状工程技术已被开发为心肌梗塞（MI）的下一代治疗方法，与直接干细胞移植和支架组织工程技术相比，具有吸引人的优势。此外，已表明诱导多能干细胞衍生细胞片比其他干细胞衍生细胞片具有更高的MI治疗潜力，因为它们具有形成血管化网络以制造增厚的人心脏组织的能力，并且具有移植后的长期治疗作用。在密歇根州。迄今为止，干细胞片移植在减轻心功能不全和改善心梗中心力衰竭的临床表现方面发挥了重要作用。在这篇评论中