Objective

To evaluate outcomes of preterm infants <26 weeks gestational age (GA) following postdelivery extensive cardiopulmonary resuscitation (ECPR) compared with airway and breathing support (ABS).

Study design

Retrospective review of Canadian Neonatal Network data during January 2010 to December 2016. The primary outcome was death or severe morbidity (intraventricular hemorrhage ≥grade 3 or periventricular leucomalacia, retinopathy of prematurity ≥stage 3, bronchopulmonary dysplasia, or necrotizing enterocolitis).

Result

Among 3633 infants analyzed, 433 (11.9%) received ECPR. In multivariable analysis, death or severe morbidity was higher in the ECPR versus ABS group [adjusted odds ratio 2.26 (95% confidence interval 1.49, 3.43)]. The majority of the difference was due to increased mortality, which occurred mostly during the first week of life.

Conclusion

These data from a recent cohort of infants near the limits of viability may be useful for prognostication for health care providers and counseling of parents.

中文翻译：

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与气道和呼吸支持相比，胎龄<26周出生的新生儿接受广泛心肺复苏的结果

客观的

评估产后广泛心肺复苏 (ECPR) 与气道和呼吸支持 (ABS) 后胎龄小于 26 周的早产儿 (GA) 的结果。

学习规划

回顾性回顾 2010 年 1 月至 2016 年 12 月期间的加拿大新生儿网络数据。主要结局是死亡或严重发病率（脑室内出血 ≥ 3 级或脑室周围白质软化、早产儿视网膜病变 ≥ 3 期、支气管肺发育不良或坏死性小肠结肠炎）。

结果

在分析的 3633 名婴儿中，433 名 (11.9%) 接受了 ECPR。在多变量分析中，ECPR 组的死亡或严重发病率高于 ABS 组 [调整优势比 2.26 (95% 置信区间 1.49, 3.43)]。大部分差异是由于死亡率增加，这主要发生在生命的第一周。

结论

这些来自最近一组接近生存极限的婴儿的数据可能有助于医疗保健提供者的预后和父母的咨询。