Cardiovascular causes have been estimated to be responsible for more than two thirds of the considerable mortality attributed to air pollution. There is now a substantial body of research demonstrating that exposure to air pollution has many detrimental effects throughout the cardiovascular system. Multiple biological mechanisms are responsible, however, oxidative stress is a prominent observation at many levels of the cardiovascular impairment induced by pollutant exposure. This review provides an overview of the evidence that oxidative stress is a key pathway for the different cardiovascular actions of air pollution.

中文翻译：

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氧化应激和空气污染对心血管的影响。

据估计，在空气污染造成的相当大的死亡率中，三分之二以上是由心血管原因造成的。现在有大量研究表明，暴露于空气污染会对整个心血管系统产生许多不利影响。多种生物学机制对此负责，然而，氧化应激是污染物暴露引起的心血管损伤的许多水平的重要观察结果。本综述概述了氧化应激是空气污染不同心血管作用的关键途径的证据。