BACKGROUND Several factors such as recipient age, BMI, serum cratinine, and positive history of dialysis are important in predicting graft survival among kidney transplant recipients. One factor affecting the transplant outcomes is donors and recipients gender, which is usually ignored. METHODS A total of 1113 kidney transplant recipients were studied in this retrospective cohort study. Several factors were taken into account for graft survival and outcomes such as donors and recipients gender and age in addition to common recipient factors like cratinine, eGFR, BMI, and positive history of dialysis. RESULTS The most successful transplant based on donor-recipient gender was observed in male donor to male recipient, and then male donor to female recipient. In female transplant recipients, level of serum cratinine and eGFR, positive dialysis history before transplant, and low donor hemoglobin level can be considered as good prognostic factors recommended for kidney transplant survival. CONCLUSIONS Our results suggested gender matching for kidney transplant. Only in some exceptional conditions, male donor to female recipient kidney transplant may be successful and female donors to male recipients are not suggested, especially in aged patients with the history of dialysis.

中文翻译：

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供体-接受者性别匹配对活体供体移植物存活的影响。

背景技术诸如受体年龄，BMI，血清肌酐和透析阳性史等多种因素在预测肾移植受体之间的移植物存活中很重要。影响移植结果的因素之一是捐赠者和接受者的性别，这通常被忽略。方法这项回顾性队列研究共研究了1113个肾移植受者。除常见的受体因素如肌酐，eGFR，BMI和透析阳性史外，还考虑了移植物存活和预后的多种因素，例如供体和受体的性别和年龄。结果观察到最成功的基于供者-接受者性别的移植，首先是男性供体到男性接受者，然后是男性供体到女性接受者。在女性移植受者中，血清肌酐和eGFR的水平 移植前透析史阳性，且供体血红蛋白水平低可被认为是推荐用于肾脏移植生存的良好预后因素。结论我们的研究结果表明肾脏移植的性别匹配。仅在某些特殊情况下，男性捐献者向女性接受者的肾脏移植才可能成功，并且不建议女性捐献给男性接受者，特别是在有透析史的老年患者中。