当前位置: X-MOL 学术Chem. Commun. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A functionalized dumbbell probe-based cascading exponential amplification DNA machine enables amplified probing of microRNAs.
Chemical Communications ( IF 4.9 ) Pub Date : 2020-01-15 , DOI: 10.1039/c9cc08289a
Jie Wang 1 , Shuhui Li , Jianguo Xu , Yusheng Lu , Min Lin , Chaihung Wang , Chen Zhang , Guoxing Lin , Lee Jia
Affiliation  

A functionalized dumbbell probe (FDP) based amplification method, termed as a cascading exponential amplification DNA machine (CEA-DNA machine), has been developed to autonomously accumulate single G-quadruplexes (SGQs) and twin-G-quadruplexes (TGQs) for robust fluorescence signal-on probing of miRNA-21.

中文翻译:

基于功能化的哑铃状探针的级联指数扩增DNA机器可对microRNA进行扩增探测。

已开发出一种基于功能化哑铃探针(FDP)的扩增方法,称为级联指数扩增DNA机(CEA-DNA机),可自动积累单个G四元体(SGQ)和双G四元体(TGQ),从而增强功能miRNA-21的荧光信号探测。
更新日期:2020-02-10
down
wechat
bug