PURPOSE Dual kidney transplantation (DKT) offers a way to extend the use of kidneys from expanded criteria donors (ECDs). Here, we compared the outcomes of DKT with those of single kidney transplantation from standard criteria donors (SCDs) and ECDs. METHODS In 2014, we began performing DKT using both kidneys from deceased donors greater than 70 years of age with one of two risk factors: serum creatinine (sCr) level over 3.0 mg/dl or eGFR under 30 ml/min. By 2017, we had performed 15 DKTs. We compared the outcomes of the 15 DKT recipients with those of 124 patients who received a kidney from an SCD and 80 patients who received a kidney from an ECD. RESULTS Compared with ECDs and SCDs, DKT donors were older, had a higher diabetes burden, and a higher sCr level (p < 0.01, < 0.01, and 0.03, respectively). DKT recipients were also older and had a higher diabetes burden than recipients of kidneys from ECDs and SCDs (p < 0.01, both). DKT recipients had a lower nadir sCr and shorter duration to nadir sCr than single ECD KT recipients (p < 0.01and 0.04, respectively). CONCLUSIONS The survival rates of DKT grafts were compatible with those of single KT grafts. Therefore, DKT may be considered a suitable an option to expand the donor pool.

中文翻译：

---

双肾移植为使用70岁以上已故供者的肾脏提供了一种安全有效的方法。

目的双肾移植（DKT）提供了一种扩展扩展标准供体（ECD）肾脏使用的方法。在这里，我们将DKT的结果与标准标准供体（SCD）和ECD的单次肾移植的结果进行了比较。方法2014年，我们开始使用来自70岁以上已故供者的两个肾脏进行DKT，其中两个风险因素之一是：血清肌酐（sCr）水平超过3.0 mg / dl或eGFR低于30 ml / min。到2017年，我们已经完成了15场DKT。我们将15位DKT接受者的结果与124位从SCD接受肾脏的患者和80位从ECD接受肾脏的患者的结果进行了比较。结果与ECD和SCD相比，DKT供体年龄更大，糖尿病负担更高，sCr水平更高（分别为p <0.01，<0.01和0.03）。与来自ECD和SCD的肾脏接受者相比，DKT接受者也年龄更大，并且糖尿病负担更高（p均<0.01）。与单个ECD KT接受者相比，DKT接受者的最低谷Cr更低，到达最低谷的持续时间更短（分别为p <0.01和0.04）。结论DKT移植物的存活率与单个KT移植物的存活率是相容的。因此，DKT可能被认为是扩大供体库的合适选择。