Megaloblastic anemia is a benign disorder characterized by ineffective hematopoiesis due to lack of vitamin B₁₂ or folate. Megaloblastic anemia could be easily treated with either vitamin B₁₂ or folate. However, a megaloblastic anemia patient may show schizocyte and hemolytic anemia with thrombocytopenia, necessitating to exclude urgent diseases like thrombotic thrombocytopenic purpura. We have experienced the vitamin B₁₂–deficient megaloblastic anemia patient mimicking thrombotic thrombocytopenic purpura. We should know the rare coexistence of hemolytic anemia with megaloblastic anemia in severe cases.

中文翻译：

---

维生素B 12缺乏的模拟肾小球血栓性血小板减少性紫癜的巨幼细胞性贫血

巨幼细胞性贫血是一种良性疾病，其特征是由于缺乏维生素B ₁₂或叶酸而导致造血功能低下。巨幼细胞性贫血很容易用维生素B ₁₂或叶酸治疗。但是，巨幼细胞性贫血患者可能会出现精神分裂症和溶血性贫血伴血小板减少症，因此必须排除血栓性血小板减少性紫癜等紧急疾病。我们曾经历过维生素B ₁₂缺乏症-巨幼细胞性贫血患者模仿​​血栓性血小板减少性紫癜。在严重的情况下，我们应该知道溶血性贫血与巨幼细胞性贫血罕见并存。