PURPOSE To investigate the outcomes of primary full-thickness macular hole (MH) after surgical intervention with tailored internal limiting membrane (ILM) flap technique. METHODS Patients were reviewed for their clinical characteristics and surgical outcomes. The technique included incomplete circular peeling of the perifoveal ILM which was then trimmed according to the size of the MH. Fluid-gas exchange was done without further manipulation. RESULTS Nineteen eyes of 19 patients were included. The patients were in average 61 years old (range 41-83) and had an average follow-up period of 11.0 months. At baseline visit, minimal linear diameter of the MH was 311.6 μm (range 80-768). After a single surgery, the MH closed in all cases with improvement of mean visual acuity (from 0.9 to 0.4 logarithm of the minimum angle of resolution units, p < 0.0001, Wilcoxon signed-rank test). At the final visit, 15 (78.9%) eyes achieved a visual acuity ≥ 20/40. Outer retinal gliosis was found to be associated with less favorable postoperative visual acuity. Factors related to the formation of outer retinal gliosis were worse preoperative visual acuity and a large MH with a diameter > 400 μm. CONCLUSION Tailored ILM flap technique is an effective method for favorable anatomical and visual outcomes for treatment of primary MH.

中文翻译：

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针对初级黄斑裂孔的量身定制的内部限制膜瓣技术。

目的探讨采用特制内部限制膜（ILM）皮瓣技术进行手术干预后的原发性全层黄斑裂孔（MH）的预后。方法对患者的临床特征和手术结局进行回顾。该技术包括对黄斑中心膜的不完全圆形剥离，然后根据MH的大小进行修整。流体-气体交换无需进一步操作即可完成。结果纳入19例患者的19眼。患者平均年龄61岁（范围41-83岁），平均随访时间为11.0个月。在基线访视时，MH的最小线性直径为311.6μm（范围80-768）。一次手术后，在所有情况下MH均关闭，平均视力有所改善（分辨力单位最小角度的对数从0.9到0.4的对数，p <0。0001，Wilcoxon秩检验）。最后一次访视时，有15（78.9％）眼的视力≥20/40。发现视网膜外胶质增生与术后视力差有关。与视网膜外神经胶质形成有关的因素是术前视力较差和直径大于400μm的大MH。结论定制的ILM皮瓣技术是治疗原发性MH的良好解剖学和视觉效果的有效方法。