Southern corn rust (SCR) is a fungal disease found on corn in several countries worldwide. In Brazil, the disease can result in productivity losses of 65%, especially in areas with a history of the disease. In this study, the genetic architecture and identification of genomic regions associated with SCR resistance was investigated by performing a genome‐wide association study. Genotyping‐by‐sequencing was performed to carry out the association between single nucleotide polymorphism (SNP) markers and phenotypic data from two environments on a panel of 164 maize inbred lines. Eight SNPs were identified as significant for SCR resistance. These SNPs were colocalized with QTL regions, some of which underlie candidate resistance genes with functions that play an important role in the stress response during pathogen recognition. These candidate genes, involved in plant defense pathways, could be associated with partial resistance to SCR and provide a partial comprehensive insight into the genetic architecture of this trait. After validation of the SNPs, they will be useful for marker–assisted selection and for a better understanding of maize resistance to SCR.

中文翻译：

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全基因组关联研究对热带玉米对南方玉米锈病的部分抗性

南部玉米锈病（SCR）是一种真菌病，在全球多个国家的玉米中均发现。在巴西，该病可能导致生产力下降65％，尤其是在有该病史的地区。在这项研究中，通过进行全基因组关联研究，研究了与SCR抗性相关的基因结构和基因组区域的鉴定。通过测序进行基因分型，以在164个玉米自交系的两个环境中进行单核苷酸多态性（SNP）标记与来自两个环境的表型数据之间的关联。八个SNP被确定对SCR抵抗显着。这些SNP与QTL区共定位，其中一些位于候选抗性基因的基础上，这些抗性基因的功能在病原体识别期间的应激反应中起重要作用。这些候选基因 参与植物防御途径的植物，可能与对SCR的部分抗性有关，并提供了对该性状遗传结构的部分全面了解。在验证了SNP之后，它们将用于标记辅助选择和更好地了解玉米对SCR的抗性。