In the present study, silk sericin–monetite microcomposites (SS–MM) were prepared using a simple and cost-effective method. Hemolytic assay was performed to determine the blood compatibility of SS–MM. MTT assay was carried out using MG-63 osteoblasts, to determine the cytocompatibility and proliferative efficacy of SS–MM. Alkaline phosphatase activity was studied to examine the osteogenic potency of the prepared microcomposites. The results obtained showed that the SS–MM can be effectively used as a bone graft for tissue engineering applications.

中文翻译：

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用于骨组织工程的丝胶和三黄磷微复合材料的制备

在本研究中，使用简单且具有成本效益的方法制备了丝胶-三氧化二磷微复合材料 (SS-MM)。进行溶血测定以确定SS-MM的血液相容性。使用MG-63成骨细胞进行MTT测定，以确定SS-MM的细胞相容性和增殖功效。研究碱性磷酸酶活性以检查制备的微复合材料的成骨效力。获得的结果表明，SS-MM 可以有效地用作组织工程应用的骨移植物。