BACKGROUND The relationship between spinal sagittal subtypes and lumbar disc degeneration is unclear. Thus, we aimed to investigate the relationship between lumbar intervertebral disc degeneration and age in asymptomatic healthy individuals with different sagittal alignments. METHODS In this cross-sectional observational study, we examined 209 asymptomatic young and middle-aged volunteers (123 women and 86 men) who were divided into the following three groups according to age: groups A (20-30 years), B (31-40 years), and C (41-50 years). The volunteers underwent full-spine standing lateral radiography and magnetic resonance imaging (MRI, 3.0 T) of the lumbar spine. Based on panoramic radiography, two observers measured the spinopelvic parameters and classified the spine into Roussouly subtypes. The degree of disc degeneration was assessed based on T2-weighted images according to the Pfirrmann classification. RESULTS There was a statistically significant difference in the degree of degeneration of type I spine between groups B and C at L4-L5 (P < 0.03) and L5-S1 (P < 0.01) and between groups A and C at L1-L2 (P < 0.04) and L4-L5 (P < 0.01). The degeneration degree of type II spine at all levels were significantly different between groups A and C. No statistically significant difference was found between groups A and B in all subtypes except for type II spine at L1-L2 (P < 0.04). A significant difference was found at four levels between groups B and C in type III spine (P < 0.05) and between groups A and C. For type IV spine, there was a significant difference in the degree of degeneration at L4-L5 (P < 0.02) between groups A and C. Moreover, almost all single parameters were not strongly correlated with the degree of disc degeneration. CONCLUSION The different spinal subtypes have characteristics of lumbar disc degeneration at specific levels with age. We considered that spinal classification could be used as a predictor of lumbar disc degeneration. Our data may be helpful to increase awareness of the relationship between spinal subtypes and lumbar disc degeneration. LEVEL OF EVIDENCE 3.

中文翻译：

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具有特定年龄水平的腰椎间盘退变特征不同的不同脊柱亚型：一项基于无症状人群的研究。

背景技术脊柱矢状亚型与腰椎间盘退变之间的关系尚不清楚。因此，我们旨在调查无矢状排列的无症状健康个体的腰椎间盘退变与年龄之间的关系。方法在这项横断面观察研究中，我们检查了209名无症状的年轻和中年志愿者（123名女性和86名男性），根据年龄将其分为以下三组：A组（20-30岁），B组（31岁） -40年）和C（41-50年）。志愿者们接受了全脊柱站立侧位放射线照相和腰椎磁共振成像（MRI，3.0 T）。基于全景射线照相，两名观察员测量了脊柱盂参数，并将脊柱分为Roussouly亚型。根据Pfirrmann分类，基于T2加权图像评估椎间盘退变的程度。结果B和C组在L4-L5（P <0.03）和L5-S1（P <0.01）以及在A1-C组在L1-L2（P <0.01）的I型脊椎退化程度有统计学差异。 P <0.04）和L4-L5（P <0.01）。A组和C组在所有水平上II型脊柱的退化程度均存在显着差异。除L1-L2处的II型脊柱外，所有亚型的A组和B组在统计学上均无统计学差异（P <0.04）。在III型脊柱的B和C组之间以及在A和C组之间的四个水平上发现了显着差异（P <0.05）。对于IV型脊柱，L4-L5的变性程度存在显着差异（P <0。02）在A组和C组之间。此外，几乎所有的单个参数都与椎间盘退变的程度没有强烈关系。结论不同的脊柱亚型在特定年龄段具有腰椎间盘退变的特征。我们认为脊柱分类可作为腰椎间盘退变的预测指标。我们的数据可能有助于提高人们对脊柱亚型与腰椎间盘退变之间关系的认识。证据级别3。我们的数据可能有助于提高人们对脊柱亚型与腰椎间盘退变之间关系的认识。证据级别3。我们的数据可能有助于提高人们对脊柱亚型与腰椎间盘退变之间关系的认识。证据级别3。