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Physical Activity and Breast Cancer: Focusing on High-Risk Subgroups and Putting Recommendations in Context.
Cancer Research ( IF 11.2 ) Pub Date : 2020-01-01 , DOI: 10.1158/0008-5472.can-19-3350
Nicole M Niehoff 1 , Alexandra J White 1 , Dale P Sandler 1
Affiliation  

While it is well-established that physical activity is associated with a decreased risk of breast cancer, most studies have been conducted in populations at an average underlying breast cancer risk. In this issue of Cancer Research, Kehm and colleagues present compelling evidence that adulthood physical activity is beneficial across the risk spectrum, including among women with BRCA1 and BRCA2 mutations. These findings are significant because women who are at a higher baseline risk are not engaging in sufficient physical activity to meet current guidelines but may be more motivated to do so knowing that they, like women in the general population, may benefit.See related article by Kehm et al., p. 116.

中文翻译:

体力活动和乳腺癌:关注高危人群,并提出相关建议。

众所周知,体育锻炼可以降低患乳腺癌的风险,但大多数研究都是在平均潜在乳腺癌风险的人群中进行的。在本期《癌症研究》中,Kehm及其同事提供了令人信服的证据,证明整个年龄的体育活动在整个风险范围内都是有益的,包括患有BRCA1和BRCA2突变的女性。这些发现具有重要意义,因为基线风险较高的女性没有进行足够的体力活动以符合当前的指南,但可能会更有动力这样做,因为她们知道自己与普通人群中的女性一样可能会受益。 Kehm et al。,p。116。
更新日期:2020-01-04
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