This introduction to the special issue of AJMG Part C: Overgrowth Syndromes updates the current understanding of overgrowth syndromes. We clarify the terminology associated with overgrowth, review some common pathways to overgrowth and present a preliminary classification based on currently known genomic and epigenetic mechanisms. We introduce the articles of this issue-new research and reviews of well-established and recently described overgrowth syndromes of the brain, body or both.

中文翻译：

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基因组时代过度生长综合症的方法。

对AJMG C部分：过度生长综合症专刊的介绍更新了对过度生长综合症的最新理解。我们阐明与过度生长有关的术语，回顾一些过度生长的常见途径，并根据当前已知的基因组和表观遗传机制提出初步分类。我们将介绍本期的最新研究文章，以及对已建立和最近描述的大脑，身体或两者的过度生长综合症的综述。