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Diagnosis and treatment of Guillain-Barré syndrome during the Zika virus epidemic in Brazil: A national survey study.
Journal of the Peripheral Nervous System ( IF 3.8 ) Pub Date : 2019-12-03 , DOI: 10.1111/jns.12358
Sonja E Leonhard 1 , Rodrigo M Conde 2 , Francisco de Assis Aquino Gondim 3 , Bart C Jacobs 1, 4
Affiliation  

The Zika virus (ZIKV) epidemic in Brazil in 2015‐2016 was followed by an increase in the incidence of patients with Guillain‐Barré syndrome (GBS). With this national survey study, we aimed to gain a better understanding of how neurologists in Brazil are currently diagnosing and treating patients with GBS, and how this increase in incidence has impacted the management of the disease. The questionnaire consisted of 52 questions covering: personal profile of the neurologist, practice of managing GBS during and outside of the ZIKV epidemic, and limitations in managing GBS. All 3264 neurologists that were member of the Brazilian Academy of Neurology at the time of the study were invited to participate. The questionnaire was fully answered by 171 (5%) neurologists. Sixty‐one percent of neurologists noticed an increase in patients with GBS during the ZIKV epidemic, and 30% experienced an increase in problems in managing GBS during this time. The most important limitations in the diagnosis and management of GBS included the availability of nerve conduction studies (NCS), beds in the Intensive Care Unit (ICU) and referral to rehabilitation centers. Most neurologists did not use a protocol for treating patients with GBS and the treatment practice varied. Increasing availability of NCS and beds in the ICU and rehabilitation centers, and the implementation of (inter)national guidelines, are critical in supporting Brazilian neurologist in their management of GBS, and are especially important in preparing for future outbreaks.

中文翻译:

巴西寨卡病毒流行期间吉兰-巴利综合征的诊断和治疗:一项全国调查研究。

2015-2016年巴西寨卡病毒(ZIKV)流行后,吉兰-巴利综合征(GBS)患者的发病率有所增加。通过这项全国性调查研究,我们旨在更好地了解巴西的神经科医生目前如何诊断和治疗 GBS 患者,以及发病率的增加如何影响该疾病的治疗。调查问卷包含 52 个问题,涵盖:神经科医生的个人简介、ZIKV 流行期间和之外管理 GBS 的实践以及管理 GBS 的局限性。研究期间巴西神经病学研究院的所有 3264 名神经科医生均受邀参加。171 名 (5%) 神经科医生完整回答了问卷。61% 的神经科医生注意到 ZIKV 流行期间 GBS 患者数量有所增加,30% 的神经科医生在此期间经历了 GBS 管理问题的增加。GBS 诊断和治疗中最重要的限制包括神经传导研究 (NCS) 的可用性、重症监护病房 (ICU) 的床位以及转诊至康复中心。大多数神经科医生没有使用治疗 GBS 患者的方案,并且治疗实践各不相同。增加 NCS 和 ICU 和康复中心床位的可用性,以及实施(国际)国家指南,对于支持巴西神经科医生管理 GBS 至关重要,对于为未来的疫情爆发做好准备尤其重要。
更新日期:2019-12-03
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