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Phenotypic heterogeneity of microbial populations under nutrient limitation.
Current Opinion in Biotechnology ( IF 7.7 ) Pub Date : 2019-11-05 , DOI: 10.1016/j.copbio.2019.09.016
Ana Gasperotti 1 , Sophie Brameyer 1 , Florian Fabiani 1 , Kirsten Jung 1
Affiliation  

Phenotypic heterogeneity is a phenomenon in which genetically identical individuals have different characteristics. This behavior can also be found in bacteria, even if they grow as monospecies in well-mixed environments such as bioreactors. Here it is discussed how phenotypic heterogeneity is generated by internal factors and how it is promoted under nutrient-limited growth conditions. A better understanding of the molecular levels that control phenotypic heterogeneity could improve biotechnological production processes.

中文翻译:

营养限制条件下微生物种群的表型异质性。

表型异质性是一种遗传上相同的个体具有不同特征的现象。即使在细菌充分混合的环境(例如生物反应器)中以单种形式生长,也可以在细菌中发现这种行为。在此讨论了表型异质性是如何由内部因素产生的,以及如何在营养受限的生长条件下促进表型异质性。对控制表型异质性的分子水平的更好理解可以改善生物技术生产过程。
更新日期:2019-11-01
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