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Morphological, hormonal, and molecular changes in different maternal tissues during lactation and post-lactation.
The Journal of Physiological Sciences ( IF 2.3 ) Pub Date : 2019-09-28 , DOI: 10.1007/s12576-019-00714-4
Gustavo Canul-Medina 1 , Cristina Fernandez-Mejia 1
Affiliation  

Milk supply and quality during lactation are critical for progeny survival. Maternal tissues and metabolism, influenced by hormonal changes, undergo modification during lactation to sustain breastfeeding. Two organs that suffer essential adjustment are the mammary glands and the bone; however, renal calcium conservation and calcium absorption from the intestine are also modified. Lactation leads to a transient loss of bone minerals to provide adequate amounts of minerals, including calcium for milk production. Physiological, metabolic, and molecular changes in different tissues participate in providing nutrients for milk production. After weaning, the histological, metabolic, and hormonal modifications that take place in lactation are reverted, and bone remineralization is a central function at this time. This study focuses on the hormonal, metabolic, molecular, and tissue modifications that occur in mammary glands, bone, intestine, and kidneys in the mother during lactation and post-weaning periods.

中文翻译:

哺乳和哺乳后不同母体组织的形态,激素和分子变化。

哺乳期间的牛奶供应和质量对于子代存活至关重要。受荷尔蒙变化影响的母体组织和新陈代谢在哺乳期间会发生变化,以维持母乳喂养。乳腺和骨骼是两个需要调节的器官。然而,肾脏钙的保守性和肠道钙的吸收也被改变。泌乳导致骨骼矿物质的短暂损失,以提供足够的矿物质,包括用于牛奶生产的钙。不同组织的生理,代谢和分子变化参与为牛奶生产提供营养。断奶后,泌乳过程中发生的组织学,代谢和激素变化恢复,骨再矿化是此时的核心功能。这项研究侧重于荷尔蒙,
更新日期:2019-11-01
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