Ca2+ is an important intracellular messenger affecting diverse cellular processes. In eukaryotic cells, Ca2+ is handled by a myriad of Ca2+-binding proteins found in organelles that are organized into the cellular reticular network (CRN). The network is comprised of the endoplasmic reticulum, Golgi apparatus, lysosomes, membranous components of the endocytic and exocytic pathways, peroxisomes, and the nuclear envelope. Membrane contact sites between the different components of the CRN enable the rapid movement of Ca2+, and communication of Ca2+ status, within the network. Ca2+-handling proteins that reside in the CRN facilitate Ca2+ sensing, buffering, and cellular signaling to coordinate the many processes that operate within the cell.

中文翻译：

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细胞网状网​​络中的细胞器钙处理。

Ca2+ 是影响多种细胞过程的重要细胞内信使。在真核细胞中，Ca2+ 由在组织成细胞网状网​​络 (CRN) 的细胞器中发现的无数 Ca2+ 结合蛋白处理。该网络由内质网、高尔基体、溶酶体、内吞和外吞途径的膜成分、过氧化物酶体和核膜组成。CRN 不同组件之间的膜接触位点能够在网络内快速移动 Ca2+ 并传递 Ca2+ 状态。驻留在 CRN 中的 Ca2+ 处理蛋白促进 Ca2+ 传感、缓冲和细胞信号传导，以协调在细胞内运行的许多过程。