The emerging paradigm in contemporary healthcare, precision medicine, is widely seen as a revolutionary approach to both clinical treatment and overall health promotion. Precision models are making use of the most up-to-date technological advancements - such as genomics and 'big data' processing - in an effort to tailor healthcare to each individual. Yet the list of hurdles to successful implementation of precision medicine is no secret. Among the challenges, it was recently suggested in this journal that we must change the 'mindset' of patients, practitioners and the wider public (McGonigle, 2016). And while precision medicine indeed demands a significant shift, we must not understate the extent of the overhaul required. In particular, I argue, against McGonigle's suggestion, that the ethical challenges regarding participant contributions cannot be tackled by relying upon existing models of incentivized blood banking or organ donation. Instead, the success of precision medicine requires a wholescale change in mindset.

中文翻译：

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改变精准医学的思维方式：从激励性生物库模型到基因组数据。

当代医疗保健，精确医学中的新兴范例被广泛视为临床治疗和整体健康促进的革命性方法。精确模型正在利用最新的技术进步，例如基因组学和“大数据”处理，以使每个人都可以定制医疗保健。然而，成功实施精密医学的障碍清单并不是秘密。在面临的挑战中，最近在该杂志上建议我们必须改变患者，从业者和广大公众的“思维定势”（McGonigle，2016年）。尽管精确医学确实需要进行重大改变，但我们绝不能低估所需的大修范围。我特别提出反对麦戈尼（McGonigle）的建议，不能依靠现有的激励性血库或器官捐赠模型来解决与参与者捐款有关的道德挑战。相反，精确医学的成功需要全面改变心态。