An approach for incorporating preliminary drug discovery research into a biochemistry laboratory is described. During a total of 42 hr (one 3‐hr laboratory section a week for 14 weeks), students were exposed to bioinformatics; molecular cloning; protein expression, purification, and characterization; and enzymatic kinetic assays. This research‐oriented laboratory not only includes the standard elements of common undergraduate biochemistry laboratory manuals but also emphasizes the logical connections among biochemistry laboratory techniques. Moreover, this approach exposed students to laboratory research and the concept of drug discovery.

中文翻译：

---

生物化学实验室潜在药物靶点克隆与表征研究的实施

描述了将初步药物发现研究纳入生物化学实验室的方法。在总共 42 小时（每周一个 3 小时的实验室部分，持续 14 周）中，学生们接触了生物信息学；分子克隆；蛋白质表达、纯化和表征；和酶动力学分析。这个研究型实验室不仅包含普通本科生化实验室手册的标准要素，而且强调生化实验室技术之间的逻辑联系。此外，这种方法让学生接触到实验室研究和药物发现的概念。