Primary progressive aphasia (PPA) is a progressive neurodegenerative disease that disrupts the language capacity of an individual by selectively affecting the language network of brain. Although aphasic literature is replete with reports of brain damage responsible for various types of PPA, it does not provide a comprehensive understanding of whether PPA is an independent pathological condition or an atypical syndrome of neurodegenerative diseases (NDD). To address this ambiguity, we provide a detailed description of PPA, its variants and their brain anatomy. Subsequently, we unravel the relationship between PPA and NDDs like Alzheimer's, Parkinson's and Dyslexia. To substantiate the relationship further, we also provide a brief account of their genetic aetiology. In the final section, we offer an exhaustive approach towards the treatment of PPA by combining the existing language the rapies with clinical and pharmacological interventions.

中文翻译：

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原发性进行性失语症和其他神经退行性疾病的语言障碍。

原发性进行性失语症（PPA）是一种进行性神经退行性疾病，通过选择性地影响大脑的语言网络来破坏个人的语言能力。尽管失语症文献中充斥着各种类型PPA引起的脑损伤的报道，但它并不能全面了解PPA是一种独立的病理状况还是神经退行性疾病（NDD）的非典型综合征。为了解决这种歧义，我们提供了PPA，其变体及其大脑解剖的详细描述。随后，我们揭开了PPA和NDD（例如阿尔茨海默氏症，帕金森氏症和诵读困难症）之间的关系。为了进一步证实这种关系，我们还简要介绍了它们的遗传病因。在最后一节中