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Computed diffusion-weighted imaging for differentiating synovial proliferation from joint effusion in hand arthritis.
Rheumatology International ( IF 4 ) Pub Date : 2019-08-27 , DOI: 10.1007/s00296-019-04425-2
Yuki Tanaka 1 , Motoshi Fujimori 1 , Koichi Murakami 2 , Hiroyuki Sugimori 3 , Nozomi Oki 4 , Takatoshi Aoki 5 , Tamotsu Kamishima 3
Affiliation  

The objective of this study is to investigate computed DWI (cDWI) as an alternative method to contrast-enhanced MRI in comparison with directory measured DWI (mDWI) and apparent diffusion coefficient (ADC) for differentiating synovial proliferation from joint effusion. Nine patients suspected with RA (5 women) were included in this study. A radiologist identified region of interest (ROI) based on STIR, and evaluated using a 5-point grading scale of 0 (fluid) to 4 (synovial proliferation) according to the degree of contrast enhancement within the ROI. cDWI was synthesized for b values from 1000 to 2000 at 200 s/mm2 intervals using the combination of b values at mDWI. In addition to ADC values, contrast ratios were calculated using signal intensity for each ROI on the mDWI and cDWI. Visual assessment by a radiologist was conducted between pairs of STIR image and mDWI or cDWI. ROI grades were most significantly correlated with cDWI2000 based on b values of 400-1000 s/mm2 (rs = 0.405, p < 0.01). The area under the curve of cDWI2000 based on b values of 400-1000 s/mm2 (0.762) was larger than that of ADC values (0.570-0.608) when comparing low versus high contrast enhancement grades. Both cDWI1800 (200-1000) and cDWI2000 (400-1000) demonstrated high sensitivity and specificity in visual assessment (84.6% and 66.7%, respectively). The cDWI2000 based on b values of 400-1000 s/mm2 may be useful for noninvasive differentiation of synovial proliferation from joint effusion in hand arthritis.

中文翻译:

计算的弥散加权成像可以区分手关节炎的滑膜增生和关节积液。

这项研究的目的是研究与位置测量的DWI(mDWI)和表观扩散系数(ADC)相比,计算出的DWI(cDWI)作为对比增强MRI的替代方法,以区分滑膜增生和关节积液。这项研究包括9名疑似RA的患者(5名女性)。放射科医生根据STIR确定了感兴趣区域(ROI),并根据ROI中对比度增强的程度,使用了0分(流体)至4分(滑膜增生)的5分等级量表进行了评估。使用mDWI的b值组合,以200 s / mm2的间隔合成bD值为1000至2000的cDWI。除了ADC值外,还使用mDWI和cDWI上每个ROI的信号强度来计算对比度。在一对STIR图像和mDWI或cDWI之间进行了放射科医生的视觉评估。基于400-1000 s / mm2的b值,ROI等级与cDWI2000最相关(rs = 0.405,p <0.01)。当比较低对比度增强等级和高对比度增强等级时,基于b值400-1000 s / mm2(0.762)的cDWI2000曲线下面积大于ADC值(0.570-0.608)。cDWI1800(200-1000)和cDWI2000(400-1000)在视觉评估中均显示出高灵敏度和特异性(分别为84.6%和66.7%)。基于b值为400-1000 s / mm2的cDWI2000可用于从手关节炎的关节积液中滑膜增生的无创性分化。0.01)。当比较低对比度增强等级和高对比度增强等级时,基于b值400-1000 s / mm2(0.762)的cDWI2000曲线下面积大于ADC值(0.570-0.608)。cDWI1800(200-1000)和cDWI2000(400-1000)在视觉评估中均显示出高灵敏度和特异性(分别为84.6%和66.7%)。基于b值为400-1000 s / mm2的cDWI2000可用于从手关节炎的关节积液中滑膜增生的无创性分化。0.01)。当比较低对比度增强等级和高对比度增强等级时,基于b值400-1000 s / mm2(0.762)的cDWI2000曲线下面积大于ADC值(0.570-0.608)。cDWI1800(200-1000)和cDWI2000(400-1000)在视觉评估中均显示出高灵敏度和特异性(分别为84.6%和66.7%)。基于b值为400-1000 s / mm2的cDWI2000可用于从手关节炎的关节积液中滑膜增生的无创性分化。
更新日期:2019-08-27
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