PURPOSE Few studies mention the necessity of antimicrobial prophylaxis (AMP) for transurethral resection of bladder tumor (TURBT) and the risk factors for postoperative urinary tract infections (UTIs) after TURBT. To evaluate the necessity of AMP and to detect the risk of UTIs, we examined the perioperative clinical factors. METHODS 687 patients who underwent TURBT between 2006 and 2017 at Hiroshima Prefectural Hospital were examined retrospectively. We defined the postoperative UTIs as febrile UTIs (≥ 38 °C). The AMP for the TURBT that we used was mostly cephalosporin generation 1. The association between the perioperative clinical/pathological factors and postoperative UTIs was assessed by logistic regression retrospectively. RESULTS 21 patients (3.1%) suffered from postoperative UTIs, and almost all of them were successfully treated with the immediate administration of antibiotics. Univariate analysis showed that past pelvic radiotherapy (p = 0.024, odds ratio (OR) 6.00), tumor size (≥ 2cm) (p = 0.008, OR 3.38), age (≥ 75 years) (p = 0.036, OR 2.65), preoperative hospital stay (≥ 5 days) (p = 0.017, OR 3.76), asymptomatic pyuria (p = 0.038, OR 2.54) and bacteriuria (p = 0.044, OR 2.97) were all associated with postoperative UTIs. CONCLUSIONS We demonstrated that AMP was effective for patients who underwent TURBT, and history of pelvic radiotherapy, high age, preoperative hospital stay and a certain tumor size were the risk factors as well as pyuria and bacteriuria of postoperative UTIs.

中文翻译：

---

经尿道膀胱肿瘤切除术后尿路感染的危险因素。

目的很少有研究提到经尿道膀胱肿瘤切除术（TURBT）的抗菌预防（AMP）的必要性以及TURBT术后尿路感染（UTI）的危险因素。为了评估AMP的必要性并检测UTI的风险，我们检查了围手术期的临床因素。方法回顾性分析2006年至2017年在广岛县立医院接受TURBT治疗的687例患者。我们将术后泌尿道感染定义为发热性泌尿道感染（≥38°C）。我们使用的TURBT的AMP主要是第1代头孢菌素。围手术期临床/病理因素与术后UTI之间的关联通过回顾性logistic回归进行了评估。结果21例患者（3.1％）患有术后UTI，几乎所有的患者都可以立即使用抗生素成功治疗。单因素分析显示，过去的骨盆放疗（p = 0.024，优势比（OR）6.00），肿瘤大小（≥2cm）（p = 0.008，OR 3.38），年龄（≥75岁）（p = 0.036，OR 2.65），术前住院（≥5天）（p = 0.017，OR 3.76），无症状性脓尿（p = 0.038，OR 2.54）和细菌尿（p = 0.044，OR 2.97）均与术后UTI相关。结论我们证明AMP对接受TURBT的患者有效，盆腔放疗史，高龄，术前住院时间和一定的肿瘤大小是术后UTI的危险因素以及脓尿和细菌尿。肿瘤大小（≥2cm）（p = 0.008，OR 3.38），年龄（≥75岁）（p = 0.036，OR 2.65），术前住院时间（≥5天）（p = 0.017，OR 3.76），无症状性脓尿（ p = 0.038，或2.54）和尿尿（p = 0.044，或2.97）均与术后UTI相关。结论我们证明AMP对接受TURBT的患者有效，盆腔放疗史，高龄，术前住院时间和一定的肿瘤大小是术后UTI的危险因素以及脓尿和细菌尿。肿瘤大小（≥2cm）（p = 0.008，OR 3.38），年龄（≥75岁）（p = 0.036，OR 2.65），术前住院时间（≥5天）（p = 0.017，OR 3.76），无症状性脓尿（ p = 0.038，或2.54）和尿尿（p = 0.044，或2.97）均与术后UTI相关。结论我们证明AMP对接受TURBT的患者有效，盆腔放疗史，高龄，术前住院时间和一定的肿瘤大小是术后UTI的危险因素以及脓尿和细菌尿。