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The aetiologies of unilateral oculomotor nerve palsy: a clinical analysis on 121 patients.
Somatosensory & Motor Research ( IF 0.9 ) Pub Date : 2019-04-30 , DOI: 10.1080/08990220.2019.1609438
Hao Chen 1 , Xiaohua Wang 1 , Shan Yao 2 , Hafiz Khuram Raza 1, 3 , Jia Jing 3, 4 , Guiyun Cui 1 , Fang Hua 1, 5
Affiliation  

Background and purpose: To strengthen the understanding, increase the early diagnostic rate, and improve the outcome of unilateral oculomotor nerve palsy through the analysis of the 121 patients suffering from this disease in our hospital. Methods: A retrospective study was performed on the 121 patients with unilateral oculomotor nerve palsy diagnosed at the Affiliated Hospital of Xuzhou Medical University from October 2014 to October 2015. The clinical data, such as gender, age, aetiology, clinical features, laboratory tests, and six months follow up reports were analyzed. Results: The main causes identified in the 121 patients with unilateral oculomotor nerve palsy were intracranial aneurysm (29.8%), diabetic peripheral neuropathy (26.5%), painful ophthalmoplegia (9.9%), and other causes (33.9%). The results from the six month follow up showed that in all the patients, 53.7% were fully recovered, 38.0% improved, and 8.3% had no significant change in symptoms. The results also indicated that the patients with diabetic peripheral neuropathy had the best outcome with 71.9% full recovery rate, which was significantly higher than that in the patients with intracranial aneurysm (36.1%, p < .05), and idiopathic causes (44.5%, p < .05). Conclusions: Our data indicates that intracranial aneurysm is the leading cause of unilateral oculomotor nerve palsy, and that diabetic peripheral neuropathy has better outcome. Understanding the common causes and clinical features of unilateral oculomotor nerve paralysis is helpful for its early diagnosis and treatment.

中文翻译:

单侧动眼神经麻痹的病因:121例临床分析。

背景与目的:通过对我院121例该病患者的分析,加深了解,提高早期诊断率,改善单侧动眼神经麻痹的疗效。方法:回顾性研究2014年10月至2015年10月在徐州医科大学附属医院诊断为单侧动眼神经麻痹的121例患者的临床资料,包括性别,年龄,病因,临床特征,实验室检查,并分析了六个月的随访报告。结果:在121例单侧动眼神经麻痹患者中发现的主要原因是颅内动脉瘤(29.8%),糖尿病周围神经病变(26.5%),疼痛性眼肌麻痹(9.9%)和其他原因(33.9%)。六个月的随访结果显示,所有患者中53.7%完全康复,38.0%改善,8.3%症状无明显改变。结果还表明,糖尿病周围神经病患者的最佳转归为71.9%,明显高于颅内动脉瘤(36.1%,p <.05)和特发性病因(44.5%)。 ,p <.05)。结论:我们的数据表明颅内动脉瘤是单侧动眼神经麻痹的主要原因,糖尿病周围神经病变的预后较好。了解单侧动眼神经麻痹的常见原因和临床特征有助于其早期诊断和治疗。3%的症状无明显变化。结果还表明,糖尿病周围神经病患者的最佳转归为71.9%,明显高于颅内动脉瘤(36.1%,p <.05)和特发性病因(44.5%)。 ,p <.05)。结论:我们的数据表明颅内动脉瘤是单侧动眼神经麻痹的主要原因,糖尿病周围神经病变的预后较好。了解单侧动眼神经麻痹的常见原因和临床特征有助于其早期诊断和治疗。3%的症状无明显变化。结果还表明,糖尿病周围神经病患者的最佳恢复率为71.9%,显着高于颅内动脉瘤(36.1%,p <.05)和特发性病因(44.5%)的患者。 ,p <.05)。结论:我们的数据表明颅内动脉瘤是单侧动眼神经麻痹的主要原因,糖尿病周围神经病变的预后较好。了解单侧动眼神经麻痹的常见原因和临床特征有助于其早期诊断和治疗。明显高于颅内动脉瘤(36.1%,p <.05)和特发性病因(44.5%,p <.05)的患者。结论:我们的数据表明颅内动脉瘤是单侧动眼神经麻痹的主要原因,糖尿病周围神经病变的预后较好。了解单侧动眼神经麻痹的常见原因和临床特征有助于其早期诊断和治疗。明显高于颅内动脉瘤(36.1%,p <.05)和特发性病因(44.5%,p <.05)的患者。结论:我们的数据表明颅内动脉瘤是单侧动眼神经麻痹的主要原因,糖尿病周围神经病变的预后较好。了解单侧动眼神经麻痹的常见原因和临床特征有助于其早期诊断和治疗。
更新日期:2019-11-01
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