当前位置: X-MOL 学术Mol. Biotechnol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Edible Vaccines: Promises and Challenges.
Molecular Biotechnology ( IF 2.6 ) Pub Date : 2020-02-01 , DOI: 10.1007/s12033-019-00222-1
Vrinda M Kurup 1 , Jaya Thomas 1
Affiliation  

Vaccines are biological preparations that improve immunity to particular diseases and form an important innovation of 19th century research. It contains a protein that resembles a disease-causing microorganism and is often made from weak or killed forms of the microbe. Vaccines are agents that stimulate the body's immune system to recognize the antigen. Now, a new form of vaccine was introduced which will have the power to mask the risk side of conventional vaccines. This type of vaccine was produced from plants which are genetically modified. In the production of edible vaccines, the gene-encoding bacterial or viral disease-causing agent can be incorporated in plants without losing its immunogenic property. The main mechanism of action of edible vaccines is to activate the systemic and mucosal immunity responses against a foreign disease-causing organism. Edible vaccines can be produced by incorporating transgene in to the selected plant cell. At present edible vaccine are developed for veterinary and human use. But the main challenge faced by edible vaccine is its acceptance by the population so that it is necessary to make aware the society about its use and benefits. When compared to other traditional vaccines, edible vaccines are cost effective, efficient and safe. It promises a better prevention option from diseases.

中文翻译:

食用疫苗:承诺和挑战。

疫苗是生物制剂,可提高对特定疾病的免疫力,并构成19世纪研究的一项重要创新。它包含一种类似于致病微生物的蛋白质,通常是由脆弱或被杀死的微生物制成。疫苗是刺激人体免疫系统识别抗原的物质。现在,一种新形式的疫苗被引入,它将有能力掩盖传统疫苗的风险方面。这种疫苗是从经过基因改造的植物中生产的。在可食用疫苗的生产中,可以将编码基因的细菌或病毒致病剂掺入植物中而不会失去其免疫原性。食用疫苗的主要作用机理是激活针对外来致病生物的全身和粘膜免疫应答。可通过将转基因掺入所选植物细胞中来生产可食用疫苗。目前,已开发出可食用的疫苗用于兽医和人类。但是食用疫苗面临的主要挑战是其被人们所接受,因此有必要使社会了解其使用和益处。与其他传统疫苗相比,可食用疫苗具有成本效益,高效且安全。它有望为疾病提供更好的预防选择。但是食用疫苗面临的主要挑战是其被人们所接受,因此有必要使社会了解其使用和益处。与其他传统疫苗相比,可食用疫苗具有成本效益,高效且安全。它有望为疾病提供更好的预防选择。但是食用疫苗面临的主要挑战是其被人们所接受,因此有必要使社会了解其使用和益处。与其他传统疫苗相比,可食用疫苗具有成本效益,高效且安全。它有望为疾病提供更好的预防选择。
更新日期:2019-11-01
down
wechat
bug