Serological tests for subclinical Mycobacterium leprae infection based on antibodies to phenolic glycolipid-1 (PGL-1) and leprosy IDRI diagnostic-1 (LID-1) have not been compared in HIV-infected and uninfected individuals. PGL-1 seropositivity by ELISA was 6.0 % (21/350) in HIV-infected compared with 29.1 % (102/350) in HIV-uninfected individuals (p < 0.001); LID-1 seropositivity was 45.4 % (159/350) in HIV-infected compared with 50.3 % (153/304) in HIV-uninfected individuals (p = 0.21). In HIV-infected individuals, LID-1 but not PGL-1 antibody levels were inversely associated with CD4+ cell count (p = 0.02). These differential associations of HIV infection and CD4 count with PGL-1 and LID-1 have implications for M leprae immunodiagnostic tools and require replication.

中文翻译：

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在巴西汉森氏病（麻风）流行地区，HIV感染和未感染HIV的个体中的PGL-1和LID-1抗体水平。

在HIV感染者和未感染者中，尚未对基于针对酚类糖脂-1（PGL-1）和麻风病I​​DRI诊断-1（LID-1）的抗体的亚临床麻风分枝杆菌感染进行血清学检测。ELISA法检测到的PGL-1血清阳性率为HIV感染者的6.0％（21/350），而未感染HIV的个体为29.1％（102/350）（p <0.001）；HIV感染者的LID-1血清阳性率为45.4％（159/350），而HIV未感染者的LID-1血清阳性率为50.3％（153/304）（p = 0.21）。在感染HIV的个体中，LID-1而非PGL-1抗体水平与CD4 +细胞计数呈负相关（p = 0.02）。HIV感染和CD4计数与PGL-1和LID-1的这些不同关联对麻痹症免疫诊断工具有影响，需要复制。