Background: Basic pathologic characteristics for farmed minks were previously reported worldwide. However, its status in the wild has not been studied in detail.

Objective: Serology and electrophoresis were carried out for evidence of exposure to 12 mink pathogens on two different locations.

Animals and methods: Serology was done in 87 wild minks by reference techniques against Toxoplasma gondii, Encephalitozoon cuniculi, Neospora caninum, Brucella abortus, Mycobacterium bovis, Leptospira interrogans, canine distemper virus (CDV), canine adenovirus (CAV), canine parvovirus (CPV), rabies virus (RV), Influenza A virus (FLUAV) and Aleutian disease virus (ADV). Hypergammaglobulinemia, the ADV main clinical feature, was determined by conventional electrophoresis.

Results: Seventy-one percent of the 87 sera had antibodies against one or more pathogens. ADV accounted for the highest seroprevalence (29%), followed by T. gondii (26%), L. interrogans (14%), M. bovis (12%), B. abortus (9%), N. caninum (3%), CPV (3%) and CDV (2%). Seroprevalence was influenced by location but not sex or age. Additionally, 16% of the seropositive samples for ADV had gammaglobulin levels >40.0 g/L. Antibody titers for CDV and CPV were low and difficult to interpret as almost all these cases had borderline concentrations.

Conclusion: A cautious interpretation of the results is urged as the epidemiological role of the wild mink is largely unexplored for most of these agents. Nevertheless, the information may be clinically relevant..

背景：以前在世界范围内都报道过养殖水貂的基本病理特征。但是，尚未对其野外地位进行详细研究。

目的：进行血清学和电泳分析，以证明在两个不同的地方暴露了12种水貂病原体。

动物和方法：通过参考技术对弓形虫，犬脑病，犬新孢子虫，流产布鲁氏菌，牛分枝杆菌，问号钩端螺旋体，犬瘟热病毒（CDV），犬腺病毒（CAV），犬细小病毒（CPV）的参考技术在87只野貂中进行了血清学检测。），狂犬病病毒（RV），甲型流感病毒（FLUAV）和阿留申氏病病毒（ADV）。高蛋白球蛋白血症（ADV的主要临床特征）通过常规电泳确定。

结果：87个血清中有71％具有针对一种或多种病原体的抗体。ADV的血清阳性率最高（29％），其次是刚地弓形虫（26％），询问乳杆菌（14％），牛分枝杆菌（12％），流产布鲁氏菌（9％），犬新孢子虫（3） ％），CPV（3％）和CDV（2％）。血清阳性率受地理位置的影响，但不受性别或年龄的影响。另外，ADV的血清反应阳性样本中有16％的球蛋白水平> 40.0 g / L。CDV和CPV的抗体滴度很低，很难解释，因为几乎所有这些病例都具有临界浓度。

结论：由于对大多数水貂的野生貂的流行病学作用尚未充分研究，因此应谨慎解释结果。但是，该信息可能与临床相关。