In the last 2-3 decades, the broad research in the application of benzimidazole derivatives made it important for mankind. Many scientists have worked on benzimidazole derivatives and they found that this compound has a diverse role in the field of medicinal chemistry. Few benzimidazole derivatives are currently in the market as a drug candidate against various diseases. Moreover, the benzimidazole derivatives exhibit pharmacological activities such as anti-tuberculosis, anti-malarial, antihistamine, antimicrobial, antiviral, antidiabetic, anticancer, anti-fungal, anti-inflammatory, analgesic, anti-HIV, etc. In this review, we have summarized various derivatives of benzimidazole which have been prepared by many researchers to understand the chemistry as well as diverse pharmacological activities. These findings may lead the scientists who are working in the field of medicinal chemistry to the development of benzimidazole based drug candidates in the future.

中文翻译：

---

苯并咪唑：药物化学领域的里程碑。

在过去的2-3年中，对苯并咪唑衍生物的广泛应用研究对人类至关重要。许多科学家研究了苯并咪唑衍生物，他们发现这种化合物在药物化学领域具有多种作用。目前，市场上很少有苯并咪唑衍生物作为抗多种疾病的候选药物。此外，苯并咪唑衍生物还具有药理活性，例如抗结核药，抗疟疾药，抗组胺药，抗微生物药，抗病毒药，抗糖尿病药，抗癌药，抗真菌药，抗炎药，镇痛药，抗HIV药等。综述了许多研究人员制备的苯并咪唑的各种衍生物，以了解其化学以及多种药理活性。