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Generalization of Object Localization From Whiskers to Other Body Parts in Freely Moving Rats.
Frontiers in Integrative Neuroscience ( IF 3.5 ) Pub Date : 2019-11-19 , DOI: 10.3389/fnint.2019.00064
David Deutsch 1 , Elad Schneidman 1 , Ehud Ahissar 1
Affiliation  

Rats can be trained to associate relative spatial locations of objects with the spatial location of rewards. Here we ask whether rats can localize static silent objects with other body parts in the dark, and if so with what resolution. We addressed these questions in trained rats, whose interactions with the objects were tracked at high-resolution before and after whisker trimming. We found that rats can use other body parts, such as trunk and ears, to localize objects. Localization resolution with non-whisking body parts (henceforth, 'body') was poorer than that obtained with whiskers, even when left with a single whisker at each side. Part of the superiority of whiskers was obtained via the use of multiple contacts. Transfer from whisker to body localization occurred within one session, provided that body contacts with the objects occurred before whisker trimming, or in the next session otherwise. This transfer occurred whether temporal cues were used for discrimination or when discrimination was based on spatial cues alone. Rats' decision in each trial was based on the sensory cues acquired in that trial and on decisions and reward locations in previous trials. When sensory cues were acquired by body contacts, rat decisions relied more on the reward location in previous trials. Overall, the results suggest that rats can generalize the idea of relative object location across different body parts, while preferring to rely on whiskers-based localization, which occurs earlier and conveys higher resolution.

中文翻译:

自由移动大鼠中从胡须到其他身体部位的对象定位的一般化。

可以训练大鼠将对象的相对空间位置与奖励的空间位置相关联。在这里,我们要问老鼠是否可以在黑暗中将静默对象与其他身体部位一起定位,如果可以,则分辨率如何。我们在训练有素的老鼠中解决了这些问题,在晶须修剪前后,都以高分辨率跟踪了它们与物体的相互作用。我们发现老鼠可以使用其他身体部位(例如躯干和耳朵)来定位对象。非须状身体部位(以下称为“身体”)的定位分辨率要比须状获得的分辨率差,即使两边只留一个须状。晶须的部分优势是通过使用多个触点获得的。在一个疗程内发生了从晶须向身体定位的转变,前提是身体与物体的接触发生在晶须修剪之前,否则发生在下一个阶段。无论是将时间线索用于辨别还是仅基于空间线索进行辨别,都会发生这种转移。在每个试验中,大鼠的决定均基于该试验中获得的感官提示以及先前试验中的决定和奖励位​​置。当通过身体接触获得感觉线索时,大鼠的决定更多地依赖于先前试验中的奖励位置。总体而言,这些结果表明,大鼠可以概括跨不同身体部位的相对对象位置的想法,而更喜欢依赖基于晶须的定位,这种定位发生得较早并且具有更高的分辨率。无论是将时间线索用于辨别还是仅基于空间线索进行辨别,都会发生这种转移。在每个试验中,大鼠的决定均基于该试验中获得的感官提示以及先前试验中的决定和奖励位​​置。当通过身体接触获得感觉线索时,大鼠的决定更多地依赖于先前试验中的奖励位置。总体而言,这些结果表明,大鼠可以概括跨不同身体部位的相对对象位置的想法,而更喜欢依赖基于晶须的定位,这种定位发生得较早并且具有更高的分辨率。无论是将时间线索用于辨别还是仅基于空间线索进行辨别,都会发生这种转移。在每个试验中,大鼠的决定均基于该试验中获得的感官提示以及先前试验中的决定和奖励位​​置。当通过身体接触获得感觉线索时,大鼠的决定更多地依赖于先前试验中的奖励位置。总体而言,这些结果表明,大鼠可以概括跨不同身体部位的相对对象位置的想法,而更喜欢依赖基于晶须的定位,这种定位发生得较早并且具有更高的分辨率。当通过身体接触获得感觉线索时,大鼠的决定更多地依赖于先前试验中的奖励位置。总体而言,这些结果表明,大鼠可以概括跨不同身体部位的相对对象位置的想法,而更喜欢依赖基于晶须的定位,这种定位发生得较早并且具有更高的分辨率。当通过身体接触获得感觉线索时,大鼠的决定更多地依赖于先前试验中的奖励位置。总体而言,这些结果表明,大鼠可以概括跨不同身体部位的相对对象位置的想法,而更喜欢依赖基于晶须的定位,这种定位发生得较早并且具有更高的分辨率。
更新日期:2019-11-01
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