Translation is the process of turning observations in the laboratory, clinic, and community into interventions that improve the health of individuals and the public, ranging from diagnostics and therapeutics to medical procedures and behavioral changes. Translational research is defined as the effort to traverse a particular step of the translation process for a particular target or disease. Translational science is a newly emerging science, distinct from basic and clinical sciences in biology and medicine, and is a field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process. Advances in translational science will increase the efficacy and safety of translational research in all diagnostic and therapeutic areas. This report examines translational research on novel hormones, the natriuretic peptide family and leptin, which have achieved clinical applications or for which studies are still ongoing, and also emphasizes the lessons that translational science has learned from more than 30 years' experience in translational research.

中文翻译：

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转化科学：生物学和医学领域的新兴科学-利钠肽家族和瘦素转化研究的经验教训。

翻译是将实验室，诊所和社区中的观察结果转变为可改善个人和公众健康的干预措施的过程，范围从诊断和治疗到医疗程序和行为改变。翻译研究被定义为针对特定目标或疾病遍历翻译过程中特定步骤的努力。转化科学是一门新兴的科学，与生物学和医学的基础科学和临床科学不同，它是一个研究领域，致力于理解转化过程每一步的科学和操作原理。翻译科学的进步将提高所有诊断和治疗领域的翻译研究的有效性和安全性。