We report a case of canine adenocarcinoma with multi-organ metastasis in which colonies of adenocarcinoma cells grew upon aerobic bacterial culture of pleural effusion. Stained agar colonies were highly similar to rare suspicious cells seen on cytologic examination of the pleural effusion, as well as rare cells seen on cytologic examination of pancreatic and gastric wall fine-needle aspirates. Cells from colonies growing on agar media were mildly immunoreactive for cytokeratin. Histologic examination of tissues obtained at autopsy revealed pancreatic adenocarcinoma with vascular invasion and nodal, gastric, pulmonary, and pleural metastasis.

中文翻译：

---

有氧细菌培养中犬胸膜液中腺癌的生长。

我们报告一例多器官转移的犬腺癌，其中有氧细菌培养的胸腔积液中腺癌细胞的菌落生长。染色琼脂菌落与在胸腔积液的细胞学检查中发现的罕见可疑细胞以及在胰腺和胃壁细针抽吸物的细胞学检查中发现的罕见细胞高度相似。来自琼脂培养基上生长的菌落的细胞对细胞角蛋白具有中等免疫反应性。尸检时对组织进行的组织学检查显示胰腺腺癌具有血管浸润以及淋巴结，胃，肺和胸膜转移。