To focus on a specific group of patients whose diagnoses were changed from unipolar depression to bipolar disorder, and finally to dementia.

中文翻译：

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特定的一组诊断为抑郁症，双相情感障碍并最终转变为痴呆的精神疾病GSK-3疾病的患者：一种假设。

将重点放在诊断从单相抑郁症变为双相情感障碍，最后变为痴呆症的特定患者群体上。