Supplemental Digital Content is Available in the Text. Background and Purpose: Fatigue is a common and debilitating symptom of multiple sclerosis (MS). Exercise therapy is effective in reducing MS-related fatigue; however, its feasibility, acceptability, and effectiveness when delivered over the telephone remain unknown. This randomized study aimed to determine the feasibility and acceptability of a telephone-delivered exercise intervention for MS-related fatigue. In addition, pre-/postchange in fatigue and secondary outcomes were compared with an otherwise identical in-person delivered exercise intervention. Methods: Twenty participants with MS and clinically significant fatigue were randomized to 8 sessions of either telephone (n = 10) or in-person (n = 10) delivered exercise therapy. Primary outcome measures concerned feasibility (number of sessions attended), acceptability (Client Satisfaction Questionnaire), and fatigue (Fatigue Severity Scale and two 11-point numeric rating scales: fatigue intensity and interference). Data on a range of secondary outcome measures were also collected. Results: There was no difference in average session attendance by group (telephone group: 7.6 ± 1.3 sessions; in-person 7.8 ± 0.42). Acceptability and reductions in fatigue were observed regardless of group, and improvements in a range of secondary outcomes were comparable. Discussion and Conclusions: A telephone-delivered exercise intervention that targets MS-related fatigue is both feasible and acceptable. Primary and secondary outcome measures signaled that telephone-delivered exercise may be an effective mode of delivery that overcomes barriers to care in persons with MS and warrants testing in larger efficacy trials. Video Abstract available for more insights from the authors (see Video, Supplemental Digital Content 1, http://links.lww.com/JNPT/A293).

中文翻译：

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呼唤 MS 疲劳

补充数字内容在文本中可用。背景和目的：疲劳是多发性硬化症 (MS) 的常见且使人虚弱的症状。运动疗法可有效减少 MS 相关的疲劳；然而，它在通过电话传送时的可行性、可接受性和有效性仍然未知。这项随机研究旨在确定电话提供的运动干预治疗 MS 相关疲劳的可行性和可接受性。此外，将疲劳和次要结果的前后变化与其他方面相同的亲自提供的运动干预进行比较。方法：20 名患有 MS 和临床显着疲劳的参与者被随机分配到 8 次电话（n = 10）或面对面（n = 10）提供的运动疗法。主要结果测量涉及可行性（参加会议的次数）、可接受性（客户满意度问卷）和疲劳（疲劳严重程度量表和两个 11 点数字评级量表：疲劳强度和干扰）。还收集了一系列次要结果指标的数据。结果：各组的平均会议出席率没有差异（电话组：7.6 ± 1.3 节；面对面 7.8 ± 0.42）。无论哪个组，都观察到可接受性和疲劳减少，并且一系列次要结果的改善具有可比性。讨论和结论：针对 MS 相关疲劳的电话提供的运动干预既可行又可接受。主要和次要结果测量表明，电话提供的锻炼可能是一种有效的提供方式，可以克服 MS 患者的护理障碍，并需要在更大规模的疗效试验中进行测试。视频摘要可提供作者的更多见解（参见视频，补充数字内容 1，http://links.lww.com/JNPT/A293）。