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Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats.
Natural Products and Bioprospecting Pub Date : 2019-10-18 , DOI: 10.1007/s13659-019-00221-4
Sohair R Fahmy 1 , Nashwah Ismail Zaki 2 , Shaimaa Zakaria Eid 1 , Ayman Saber Mohamed 1 , Sarah S Hassanein 1
Affiliation  

Obesity has been identified with an expanded danger of a progression of illnesses that include different organ-frameworks of the body. In the present examination, we evaluated the hypolipidemic properties of Echinochrome (Ech) pigment in a high-fat diet (HFD) induced hyperlipidemia in rats. After the hyperlipidemic model was set up, rats were haphazardly separated into five groups as follows: normal control group, HFD group, Atorvastatin (ATOR) group (80 mg/kg), Ech group (1 mg/kg) and combined group ATOR + Ech. The outcomes demonstrated that Ech improves lipid profile, liver functions, kidney functions and antioxidant markers of obese rats. The findings of the present investigation indicated that the Ech possesses hypolipidemic potential in obese rats.

中文翻译:

Echinochrome对HFD诱导的大鼠高脂血症的作用。

肥胖已被确定为疾病发展的更大危险,其中包括身体的不同器官结构。在本次检查中,我们评估了高脂饮食(HFD)诱导的大鼠高脂血症中棘手色素(Ech)色素的降血脂特性。建立高脂血症模型后,将大鼠随机分为五组:正常对照组,HFD组,阿托伐他汀(ATOR)组(80 mg / kg),Ech组(1 mg / kg)和联合组ATOR +嗯 结果表明,Ech可改善肥胖大鼠的脂质分布,肝功能,肾功能和抗氧化剂。本研究的发现表明,Ech在肥胖大鼠中具有降血脂的潜力。
更新日期:2019-10-18
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