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Profit considerations in vaccine safety-related events in China.
Expert Review of Vaccines ( IF 6.2 ) Pub Date : 2019-11-13 , DOI: 10.1080/14760584.2019.1688150 Jianlin Zhuang 1, 2 , Yihan Lu 1 , Abram L Wagner 3 , Qingwu Jiang 1
Expert Review of Vaccines ( IF 6.2 ) Pub Date : 2019-11-13 , DOI: 10.1080/14760584.2019.1688150 Jianlin Zhuang 1, 2 , Yihan Lu 1 , Abram L Wagner 3 , Qingwu Jiang 1
Affiliation
Objectives: China has made remarkable achievements in the field of immunization. However, several widespread vaccine safety-related events have recently received worldwide attention and reflect flaws in vaccine management. This study aimed to summarize vaccine safety-related events between 1985 and 2018 in China and analyze the profit motives of these events.Methods. Literature and media reviews were conducted to discover vaccine safety-related events. We developed a conceptual model with profit-related variables, and using information available from each event, we identified which profit-related variable was implicated, and how it related to the pursuit of higher profits.Results: A total of 39 vaccine safety-related events were found in vaccine production, procurement, transportation, and daily management, along with adverse events following immunization (AEFIs). Overall, 90% (35/39) of the events could be classified as profit-driven. The motives of most events could be tied to one or more reasons, including decreasing costs among vaccine producers (67%, 26/39), reducing actual procurement price (67%, 26/39), and reducing costs of transportation and/or cold chain (24/39, 62%).Conclusions: In order to deal with vaccine-related challenges, a more restrictive supervision system on vaccine production and more emergency preparedness, including health and risk communication strategies, for vaccine safety should be implemented.
更新日期:2019-11-01