BACKGROUND Diabetes mellitus is the most common metabolic disorder amongst dental patients. The association between the diabetes and the outcome of root canal treatment is unclear. AIM To conduct an umbrella review to determine whether there is an association between diabetes and the outcome of root canal treatment. DATA SOURCE The protocol of the review was developed and registered in the PROSPERO database (CRD42019141684). Four electronic databases (PubMed, EBSCHOhost, Cochrane and Scopus databases) were used to perform a literature search until July 2019. STUDY ELIGIBILITY CRITERIA, PARTICIPANTS AND INTERVENTIONS Systematic reviews with or without meta-analyses published in English assessing any outcomes of root canal treatment comparing diabetic and nondiabetic patients were included. Two reviewers were involved independently in study selection, data extraction and appraising the reviews that were included. Disagreements were resolved with the help of a third reviewer. STUDY APPRAISAL AND SYNTHESIS METHODS The quality of the reviews was assessed using the AMSTAR tool (A measurement tool to assess systematic reviews), with 11 items. Each AMSTAR item was given a score of 1 if the criterion was met, or 0 if the criterion was not met or the information was unclear. RESULTS Four systematic reviews were included. The AMSTAR score for the reviews ranged from 5 to 7, out of a maximum score of 11, and all the systematic reviews were classified as 'medium' quality. LIMITATIONS Only two systematic reviews included a meta-analysis. Only systematic reviews published in English were included. CONCLUSIONS AND IMPLICATIONS OF KEY FINDINGS Diabetes mellitus is associated with the outcome of root canal treatment and can be considered as a preoperative prognostic factor.

中文翻译：

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糖尿病与成人根管治疗结果之间的关联：综合评价。

背景技术糖尿病是牙科患者中最常见的代谢紊乱。糖尿病与根管治疗结果之间的关系尚不清楚。目的 进行全面审查以确定糖尿病与根管治疗结果之间是否存在关联。数据来源 审查方案是在 PROSPERO 数据库 (CRD42019141684) 中开发和注册的。使用四个电子数据库（PubMed、EBSCHOhost、Cochrane 和 Scopus 数据库）进行文献检索，直至 2019 年 7 月。研究资格标准、参与者和干预措施包括糖尿病和非糖尿病患者。两名审查员独立参与研究选择、数据提取和评估纳入的审查。在第三位评审员的帮助下解决了分歧。研究评价和综合方法 使用 AMSTAR 工具（评估系统评价的测量工具）对评价的质量进行评估，共有 11 个项目。如果满足标准，则每个 AMSTAR 项目得分为 1，如果不满足标准或信息不明确，则为 0。结果 包括四项系统评价。评论的 AMSTAR 评分范围为 5 到 7，最高分为 11 分，所有系统评论都被归类为“中等”质量。局限性 只有两个系统评价包括荟萃分析。仅包括以英文发表的系统评价。