Through his own research contributions on the modelling and genetic analysis of quantitative traits and through his former students and postdocs, Robin Thompson has indirectly left a major legacy in human genetics. In this short note, we highlight examples of the long-lasting relevance and impact of Robin's work in human genetics. A lone early study of marker-assisted selection developed many of the tools and approaches later exploited (often after reinvention) by the human genetics community in GWAS studies and for prediction. Furthermore, a particularly clear example of the pervasive impact of Robin's work is that REML has become the default method to estimate variance components and that genetic predictions exploiting linkage disequilibrium in the population are starting to become used in precision medicine applications.

中文翻译：

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“艺术与劳动”——布莱克本流浪者球迷在人类复杂性状遗传学方面的遗产

通过他自己在数量性状建模和遗传分析方面的研究贡献，以及通过他以前的学生和博士后，罗宾·汤普森间接地在人类遗传学方面留下了重大遗产。在这篇简短的笔记中，我们重点介绍了罗宾在人类遗传学方面的工作的长期相关性和影响的例子。一项单独的早期标记辅助选择研究开发了许多工具和方法，后来被人类遗传学界在 GWAS 研究和预测中利用（通常在重新发明之后）。此外，Robin 工作普遍影响的一个特别明显的例子是，REML 已成为估计方差分量的默认方法，并且利用群体中连锁不平衡的遗传预测开始用于精准医学应用。