The present study supports the usefulness of ancillary techniques, such as immunohistochemistry, as a valid diagnostic tool in the field of fish oncology. The immunohistochemical patterns observed in four neoplasms on four individual teleosts belonging to different species are described. Cytokeratin, vimentin, actin, S100, calretinin, and Melan-A antibodies were used. Diagnoses of papilloma in a Bream Abramis brama, fibroma in a Sand Steenbras Lithognathus mormyrus, schwannoma in a Crucian Carp Carassius carassius, and melanoma in a spontaneously inbred Xiphophorus hybrid were made. Diagnosis of tumors in fish is not always easy to carry out, and the tool provided by antibodies used on mammalian tissue is essential for obtaining definitive, unambiguous, and inexpensive identification.

中文翻译：

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四种鱼类肿瘤的免疫组化研究

本研究支持辅助技术（如免疫组织化学）作为鱼类肿瘤学领域的有效诊断工具的有用性。描述了在属于不同物种的四个个体硬骨鱼的四个肿瘤中观察到的免疫组织化学模式。使用细胞角蛋白、波形蛋白、肌动蛋白、S100、钙视网膜蛋白和 Melan-A 抗体。诊断出鲂 Abramis brama 中的乳头状瘤、Sand Steenbras Lithognathus mormyrus 中的纤维瘤、Crucian Carp Carassius carassius 中的神经鞘瘤和自发近交剑齿鱼杂种中的黑色素瘤。鱼类肿瘤的诊断并不总是容易进行，哺乳动物组织上使用的抗体所提供的工具对于获得明确、明确且廉价的鉴定至关重要。