We summarize and discuss issues that emerged from a workshop entitled 'Human and Animal Neurotoxicology-From Exposure to Great Lakes Pollutants' that was held as part of the May 2000 Annual Meeting of the International Association of Great Lakes Research in Cornwall, Ontario, Canada. The most apparent and distressing finding was the lack of communication that currently exists between scientists of different sub-disciplines-including in vitro and in vivo toxicologists, epidemiologists and risk assessors. Although all participants agreed that integrated, multi-disciplinary research is the only avenue that offers a realistic chance of identifying, characterizing and eventually preventing the adverse consequences of developmental exposure to neurological and reproductive toxicants, there was little consensus on how to achieve this goal. We leave to the readers of this Special Issue of Environmental Toxicology and Pharmacology the daunting task of implementing the greater degree of communication needed to begin to solve problems due to developmental exposure to environmental contaminants.

中文翻译：

---

鱼源性有毒物质的后果和作用机制：我们不知道的原因以及原因。

我们总结并讨论了题为“人类和动物神经毒理学-从暴露到大湖污染物”的研讨会提出的问题，该研讨会是2000年5月在加拿大安大略省康沃尔市国际大湖研究协会年会的一部分。最明显和令人不安的发现是，目前不同学科的科学家之间缺乏沟通，包括体外和体内毒理学家，流行病学家和风险评估者。尽管所有参与者都认为，综合的，多学科的研究是唯一的途径，可以为鉴定，表征和最终预防发育性暴露于神经毒物和生殖毒物的不良后果提供现实的机会，但对于如何实现这一目标却几乎没有共识。