Patients who have suffered a single clinical lacunar syndrome, in the absence of any previous clinical stroke, have a varying neuroradiological profile. We examined general cognition in 30 nonaphasic first-ever lacunar syndrome participants, using a battery of standard clinical neuropsychological measures. At a group level, stroke participants did not demonstrate any cognitive impairment relative to well-matched community-based controls up to 12 months after stroke. There was also no evidence of increased frequencies of mild cognitive impairment after a single clinical lacunar syndrome relative to matched control participants within the first year post-stroke. The current findings represent the first investigation of the cognitive outcome of nonaphasic individuals who have a first-ever clinical lacunar syndrome. It was concluded that a clinically diagnosed first ever stroke event, presenting as a lacunar syndrome, was not associated with an elevated risk of developing mild cognitive impairment 12 months post-stroke.

中文翻译：

---

首次出现腔隙性梗塞综合征的临床表现的个体：中风后的前12个月是否会出现轻度认知障碍？

在没有任何先前的临床卒中的情况下患有单一临床腔隙综合征的患者，其神经放射学特征有所不同。我们使用了一系列标准的临床神经心理学方法，对30名非相伴首例腔隙综合征参与者的一般认知进行了检查。在小组水平上，中风参与者直到中风后12个月都没有表现出与良好匹配的社区对照相比的任何认知障碍。也没有证据表明在卒中后的第一年内，相对于相匹配的对照参与者，单一临床腔隙综合征后轻度认知障碍的发生率增加。目前的发现代表首次对患有非临床性腔隙综合征的非失语症患者认知结果的首次调查。