Deinococcus radiodurans, one of the most radioresistant organisms known to date, is able to repair efficiently hundreds of DNA double- and single-strand breaks as well as other types of DNA damages promoted by ionizing or ultraviolet radiation. We review recent discoveries concerning several aspects of radioresistance and survival under high genotoxic stress. We discuss different hypotheses and possibilities that have been suggested to contribute to radioresistance and propose that D. radiodurans combines a variety of physiological tools that are tightly coordinated. A complex network of regulatory proteins may be discovered in the near future that might allow further understanding of radioresistance.

中文翻译：

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放射性球菌：什么属于生存工具包？

Deinococcus radiodurans是迄今为止已知的最耐辐射的生物之一，能够有效修复数百个DNA双链和单链断裂以及电离或紫外线辐射引起的其他类型的DNA损伤。我们回顾了有关在高遗传毒性胁迫下抗辐射性和存活率几个方面的最新发现。我们讨论了已经提出的有助于抗辐射性的不同假设和可能性，并提出了D. radiodurans结合了多种紧密协调的生理工具。在不久的将来可能会发现一个复杂的调节蛋白网络，这可能会使人们进一步了解放射抗性。