To help identify the role of modelling and simulation in the development of anti-cancer agents, their main advantages and the obstacles to their rational use, an expert meeting was organized by COST B15. This manuscript presents a synthesis of views expressed at that meeting and indicates future directions. The manuscript also shows some examples where modelling and simulation have proven to be of relevant value in the drug development process for anti-cancer agents.

中文翻译：

---

在开发和使用抗癌药物中进行建模和仿真：使用不足的工具？

为了帮助确定建模和仿真在抗癌药开发中的作用，其主要优点以及合理使用它们的障碍，COST B15组织了一次专家会议。该手稿介绍了该次会议上表达的观点并指出了未来的方向。该手稿还显示了一些实例，其中建模和仿真已证明在抗癌药的药物开发过程中具有相关价值。