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Coding-complete genome sequencing suggests that Newcastle disease virus challenge strain Herts'33 (IVMP) may represent a distinct genotype.
Archives of Virology ( IF 2.7 ) Pub Date : 2019-11-08 , DOI: 10.1007/s00705-019-04441-4
Enikő Fehér 1 , Ádám Bálint 2 , Szilvia Marton 1 , Krisztina Bali 1 , Sándor Belák 3 , Krisztián Bányai 1
Affiliation  

We determined the genomic sequence of a Newcastle disease virus (NDV) line obtained directly from the first NDV isolate, named Herts'33. This strain shared ≤ 90% nucleotide sequence identity with the NDV sequences available in the GenBank database, and formed a distinct branch in a phylogenetic tree. This branch may be considered to represent a separate NDV genotype. Our study indicates that investigation of the genomic sequences of old NDV strains that originated from the early outbreaks of Newcastle disease may alter the phylogenetic grouping of the NDV strains and provide data on the evolution of viral genomes over time.

中文翻译:

编码完成的基因组测序表明,新城疫病毒攻击株Herts'33(IVMP)可能代表独特的基因型。

我们确定了直接从第一个NDV分离株Herts'33直接获得的新城疫病毒(NDV)系的基因组序列。该菌株与GenBank数据库中的NDV序列具有≤90%的核苷酸序列同一性,并在系统树中形成了独特的分支。该分支可被认为代表单独的NDV基因型。我们的研究表明,对源自新城疫早期爆发的旧NDV毒株的基因组序列进行调查可能会改变NDV毒株的系统发育分组,并提供有关病毒基因组随时间演变的数据。
更新日期:2020-01-13
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